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上海允麥生物科技有限公司
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Recombinant human VRK1 protein
PCH1; Serine/threonine protein kinase VRK1; Serine/threonine-protein kinase VRK1; Vaccinia related kinase 1; Vaccinia virus B1R related kinase 1; Vaccinia-related kinase 1; VRK1; VRK1_HUMAN; MGC117401; MGC138280; MGC142070
濃度：1mg/ ml
來(lái)源：Recombinant Human
純度：≥95% SDS-PAGE
表達(dá)系統(tǒng)：Baculovirus infected Sf9 cells
蛋白長(zhǎng)度：Full length protein
內(nèi)毒素水平：<1.000 Eu/µg
純化方法：HPLC
應(yīng)用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保質(zhì)期：1年
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
產(chǎn)品名稱：Rabbit Anti-VRK1 protein antibody
Rabbit Anti-VRK1 protein
別名：PCH1; Serine/threonine protein kinase VRK1; Serine/threonine-protein kinase VRK1; Vaccinia related kinase 1; Vaccinia virus B1R related kinase 1; Vaccinia-related kinase 1; VRK1; VRK1_HUMAN; MGC117401; MGC138280; MGC142070
來(lái)源：Rabbit
克隆類型：Polyclonal
濃度：1mg/ml
亞型：IgG
反應(yīng)：(predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse)
應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
理論分子量：45kDa
免疫原：KLH conjugated synthetic peptide derived from human VRK1 protein
保存：-20℃
保質(zhì)期：1年
產(chǎn)品名稱：Anti-VRK1 protein antibody
Mouse Anti-VRK1 protein
別名：PCH1; Serine/threonine protein kinase VRK1; Serine/threonine-protein kinase VRK1; Vaccinia related kinase 1; Vaccinia virus B1R related kinase 1; Vaccinia-related kinase 1; VRK1; VRK1_HUMAN; MGC117401; MGC138280; MGC142070
來(lái)源：Mouse
克隆類型：Monoclonal
濃度：1mg/ml
亞型：IgG
反應(yīng)：Human
應(yīng)用：WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應(yīng): Human
理論分子量：45kDa
免疫原：KLH conjugated synthetic peptide derived from human VRK1
保存：-20℃
保質(zhì)期：1年
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
