聯(lián)系電話
上海允麥生物科技有限公司
中級(jí)會(huì)員·7年
- 聯(lián)系人：
- 麥經(jīng)理
- 電話：
- 86-021-34553900
- 手機(jī)：
- 15121004110
- 傳真：
- 86-021-34553900
- 地址：
- 上海市青浦區(qū)
- 個(gè)性化：
- www.shymbio.com
- 網(wǎng)址：
- www.shymbio.com
掃一掃訪問手機(jī)商鋪
 提 供 商 |
上海允麥生物科技有限公司 |  資料大小 |
31.5KB |
|---|---|---|---|
 資料類型 |
JPG 圖片 |  資料圖片 |
|
 下載次數(shù) |
0次 |  瀏覽次數(shù) |
161次 |
Recombinant human Wnt16
Protein Wnt 16 precursor; Protein Wnt-16; Wingless type MMTV integration site family member 16; WNT16; WNT16_HUMAN.
濃度：1mg/ ml
來源：Recombinant Human
純度：≥95% SDS-PAGE
表達(dá)系統(tǒng)：Escherichia coli
標(biāo)簽：His tag
蛋白長度：Full length protein
內(nèi)毒素水平：<1.000 Eu/µg
純化方法：HPLC
應(yīng)用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保質(zhì)期：1年
The Wnt genes encode a family of secreted extracellular signaling glycoproteins, which function in a variety of important developmental processes such as regulation of cell growth and differentiation. Wnt proteins also play roles in carcinogenesis. Wnt-14, rather than Wnt-15, is preferentially expressed in various types of human cancer. Wnt-15 is expressed in fetal and adult kidney and is most homologous to Wnt-14. Wnt-16, another member in the Wnt family, has two mRNA isoforms, Wnt-16a and Wnt-16b. These isoforms differ in the composition of their 5'UTR and first exon, which results in differential expression. Wnt-16a is expressed only in pancreas, whereas Wnt-16b is highly expressed in adult kidney, placenta, brain, heart and spleen, but not in bone marrow. However, Wnt-16 transcripts are present in bone marrow and cell lines derived from pre-B acute lymphoblastoid leukemia patients carrying the E2A-Pbx1 hybrid gene. Thus, Wnt-16 is a downstream target of E2A-Pbx1, and the Wnt-16-mediated autocrine growth mechanism may contribute to the development of t(1;19) pre-B acute lymphoblastoid leukemias.
產(chǎn)品名稱：Rabbit Anti-Wnt16 antibody
Rabbit Anti-Wnt16
別名：Protein Wnt 16 precursor; Protein Wnt-16; Wingless type MMTV integration site family member 16; WNT16; WNT16_HUMAN.
來源：Rabbit
克隆類型：Polyclonal
濃度：1mg/ml
亞型：IgG
反應(yīng)：Human (predicted: Mouse,Rat,Rabbit,Pig,Cow)
應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
理論分子量：37kDa
免疫原：KLH conjugated synthetic peptide derived from human Wnt16
保存：-20℃
保質(zhì)期：1年
產(chǎn)品名稱：Anti-Wnt16 antibody
Mouse Anti-Wnt16
別名：Protein Wnt 16 precursor; Protein Wnt-16; Wingless type MMTV integration site family member 16; WNT16; WNT16_HUMAN.
來源：Mouse
克隆類型：Monoclonal
濃度：1mg/ml
亞型：IgG
反應(yīng)：Human
應(yīng)用：WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應(yīng): Human
理論分子量：37kDa
免疫原：KLH conjugated synthetic peptide derived from human Wnt16
保存：-20℃
保質(zhì)期：1年
The Wnt genes encode a family of secreted extracellular signaling glycoproteins, which function in a variety of important developmental processes such as regulation of cell growth and differentiation. Wnt proteins also play roles in carcinogenesis. Wnt-14, rather than Wnt-15, is preferentially expressed in various types of human cancer. Wnt-15 is expressed in fetal and adult kidney and is most homologous to Wnt-14. Wnt-16, another member in the Wnt family, has two mRNA isoforms, Wnt-16a and Wnt-16b. These isoforms differ in the composition of their 5'UTR and first exon, which results in differential expression. Wnt-16a is expressed only in pancreas, whereas Wnt-16b is highly expressed in adult kidney, placenta, brain, heart and spleen, but not in bone marrow. However, Wnt-16 transcripts are present in bone marrow and cell lines derived from pre-B acute lymphoblastoid leukemia patients carrying the E2A-Pbx1 hybrid gene. Thus, Wnt-16 is a downstream target of E2A-Pbx1, and the Wnt-16-mediated autocrine growth mechanism may contribute to the development of t(1;19) pre-B acute lymphoblastoid leukemias.
