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上海允麥生物科技有限公司
中級(jí)會(huì)員·7年
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- 麥經(jīng)理
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- 86-021-34553900
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- 15121004110
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- 86-021-34553900
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- www.shymbio.com
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Recombinant human Wnt receptor
Frizzled-1; Frizzled homolog 1 (Drosophila); Fz1; hFz1; Fz-1; FZD1; FzE1; Wnt receptor; FZD1_HUMAN.
濃度：1mg/ ml
來(lái)源：Recombinant Human
純度：≥95% SDS-PAGE
表達(dá)系統(tǒng)：Escherichia coli
標(biāo)簽：His tag
蛋白長(zhǎng)度：Full length protein
內(nèi)毒素水平：<1.000 Eu/µg
純化方法：HPLC
應(yīng)用：SDS-PAGE，Western blot，ELISA
Biological activity,immunology research
保存：-20℃
保質(zhì)期：1年
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK3 kinase, nuclear accumulation of beta catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt mediated inactivation of GSK3 kinase. Both pathways seem to involve interactions with G proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.
產(chǎn)品名稱：Rabbit Anti-Wnt receptor antibody
Rabbit Anti-Wnt receptor
別名：Frizzled-1; Frizzled homolog 1 (Drosophila); Fz1; hFz1; Fz-1; FZD1; FzE1; Wnt receptor; FZD1_HUMAN.
來(lái)源：Rabbit
克隆類型：Polyclonal
濃度：1mg/ml
亞型：IgG
反應(yīng)：Human,Rat (predicted: Mouse,Pig,Cow,Chicken,Dog,Horse)
應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
免疫原：KLH conjugated synthetic peptide derived from human Wnt receptor
保存：-20℃
保質(zhì)期：1年
產(chǎn)品名稱：Anti-Wnt receptor antibody
Mouse Anti-Wnt receptor
別名：Frizzled-1; Frizzled homolog 1 (Drosophila); Fz1; hFz1; Fz-1; FZD1; FzE1; Wnt receptor; FZD1_HUMAN.
來(lái)源：Mouse
克隆類型：Monoclonal
濃度：1mg/ml
亞型：IgG
反應(yīng)：Human
應(yīng)用：WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應(yīng): Human
免疫原：KLH conjugated synthetic peptide derived from human Wnt receptor
保存：-20℃
保質(zhì)期：1年
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK3 kinase, nuclear accumulation of beta catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt mediated inactivation of GSK3 kinase. Both pathways seem to involve interactions with G proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.
