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HORIBA科學(xué)儀器事業(yè)部

HORIBA網(wǎng)絡(luò)講座|SPRI在抗體的運用

時間:2017-9-27 閱讀:311
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Live Webinar

Tuesday, October 3

16 PM/ 23 PM GMT/UTC

 

This webinar will show the potentialities of the new multiplexing and fully automated SPRi "XelPleX" by illustrating

two examples of the simultaneous characterization of multiple biologically relevant interactions.

 

The first example represents the discovery and the study of the interaction between the endogenous antimicrobial peptide cathelicidin (LL37) and different beta-amyloid aggregation forms spotted onto the SPRi chip surface. This study confirms that cathelicidin is a binding partner of beta-amyloid and suggests its potential role as inhibitor of beta-amyloid fibrils.

 

The second example concerns the development and the optimization of a peptide microarray for the detection of circulating IgE antibodies in milk allergic patients. SPRi measurements permitted to select the best epitope presentation strategy (i.e. multiple epitope presentation) in order to obtain optimal analytical performances.

 

Key Learning Objectives

 

  • Learning how the SPRi platform provides flexibility to scientists to engineer a wide range of assays for the detection of various analytes at real time, simultaneously and with high throughput

  • Learn how to choose whether to perform kinetic or equilibrium SPR analyses

  • Learn how to perform kinetic analyses of high-affinity antibody/antigen interactions

 

Who Should Attend?

 

  • Academic and industrial researchers working with and developing bioassays for a wide range of analytes.

  • Scientists specializing or have expertise in the following fields: biomedical and clinical science, proteomics, genomics, biochemistry, ...

 

Presented by

 

Dr Renzo Vanna, Researcher at IRCCS Fondazione Don Carlo Gnocchi, Laboratory of nanomedicine and clinical biophotonics (LABION),Milan, Italy Moderated by

 

Dr Chiraz Frydman, SPRi Product Manager at HORIBA Scientific

 

Register Now!

 

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HORIBA Optical School

HORIBA一直致力于為用戶普及光譜基礎(chǔ)知識,其旗下的Jobin Yvon有著近200年的光學(xué)、光譜經(jīng)驗,我們非常樂意與大家分享這些經(jīng)驗,為此特創(chuàng)立 Optical School(光譜學(xué)院)。無論是剛接觸光譜的學(xué)生,還是希望有所建樹的研究者,都能在這里找到適合的資料及課程。 

 

我們希望通過這種分享方式,使您對光學(xué)及光譜技術(shù)有更系統(tǒng)、全面的了解,不斷提高儀器使用水平,解決應(yīng)用中的問題,進而提升科研水平,更好地探索未知世界。

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