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Fast separation of FAME isomers from Sunflower oil The new FactorFour VF-23ms bonded phase is a new highly polar phase with high cyano substitution having an optimized stabilization structure. Combined with fused silica surface treatment a temperature stability of up to 260°C isothermally was realized which results in very low bleed. Accurate quantification of trace components as well as fast stabilization and reduced contamination of detection systems (like ms) are obtained. Due to the high cyano content and the special bonding technology, this phase is very stable.